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Clinical manifestations of hypothyroidism secondary to Hashimoto's disease include: Fatigue and lethargy Weight gain despite normal appetite Cold intolerance Dry skin and hair loss Constipation Depression and cognitive impairment Bradycardia and elevated cholesterol Diagnosis is established through thyroid function tests showing elevated thyroid-stimulating hormone (TSH) with low free T4 (overt hypothyroidism) or normal free T4 (subclinical hypothyroidism), alongside positive thyroid antibodies

If you do miss one or accidentally double up, call your provider to find out what you should do.

When appetite regulation stabilizes, the blood sugar rollercoaster that causes energy crashes flattens out

Diabetologia 65 , 11451156 (2022)

Gastrointestinal side effects led to treatment discontinuation in 10% of semaglutide patients versus 2% on placebo, though serious adverse events were actually less frequent with semaglutide (33.4% vs 36.4%)

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