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Inflammatory Bowel Disease (IBD): Conditions such as ulcerative colitis and Crohns disease can cause inflammation and ulcers in the digestive tract, leading to anorectal bleeding
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In addition, several effects of incretin-based diabetes therapies beyond their glycemic-lowering properties via the endocrine pancreas have been described, including reduced immune cell infiltration and altered cytokine expression (66)
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Glycaemic control and beta cell function in type 2 diabetes on SGLT2i and GLP-1RA combination therapy [abstract]