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By the end of the treatment, the paw thickness of treated animals decreased to less than half of that observed in the untreated control group, and clinical scores were significantly improved, matching the efficacy of subcutaneous melittin administration ( A key innovation in this approach is the incorporation of methacrylate-modified HA (MeHA), enabling sustained release of melittin

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Arch Biochem Biophys 536(2):101108

Vitamin C, known for its potent antioxidant properties, is crucial in alleviating oxidative stress and potentially mitigating the progression of IBD

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Compared to the more exposed copper-binding site in mTYR, the pocket of hTYR offers more space for arbutin to adopt various orientations