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Many people discover they are eating far less protein than they assumed, or consuming far fewer calories than their body needs

DOI: [4] Sinha R, Sinha I, Calcagnotto A, Trushin N, Haley JS, Schell TD, et al

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These effects are initially mediated by natriuresis and plasma volume contraction, but sustained effects likely reflect additional mechanisms including reduced total body sodium, decrease in intracellular sodium and calcium, and vasodilation

doi: 10.1177/1559827616637066 136

demonstrated that, under physiological conditions, macrophages could, uptake native Hb without the binding protein Hp through CD163 (Schaer et al., 2006)