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doi:10.3390/biology14050575

If most of the drug is gone, you may experience side effects if you resume the medicine at your regular dose

[17] Trials can be identified via the NIHR 'Be Part of Research' portal, ClinicalTrials.gov, or the ISRCTN registry

During the first week, its normal to experience a gradual reduction in hunger and an increase in feelings of fullness, but the appetite-suppressing effects may take some time to become fully apparent