Gastrointestinal adverse events, principally nausea, diarrhea, and vomiting, were the most frequently reported findings, consistent with the incretin-agonist class
Preparation: There is no special preparation required before starting treatment, although maintaining a healthy lifestyle is encouraged
Metformin modestly supports weight loss through improved insulin sensitivity, while GLP-1 directly suppresses appetite and increases satietythe combination amplifies both mechanisms
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Adults ages 4554 had the highest initiation rate ( 91 per 1,000 patients with OSA ), followed by ages 35-44 ( 87 per 1,000 )
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