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Interestingly, the GPX4 inhibitor RSL3 can impair the maturation and function of DCs in tumor suppression by activating PPARG/PPAR (peroxisome oroliferator activated receptor gamma)-dependent ferroptosis in DC2.4 cell line [195] (Fig

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However, because these drugs carry costs, side effects, and access issues, botanicals that can support endogenous GLP-1 activity are attractive as adjunctive options

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