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Few ideal properties of the drug that can be administered transdermally require that drug should be essentially non-irritating, dose should be preferably up to 20 mg or less and partition coefficient in octanol / water should be between 1 to 4

You can also try relieving the itch by applying cool, wet compresses to the rash and layering on an over-the-counter corticosteroid cream, according to the Food and Drug Administration (FDA)

Papamargaritis D, le Roux CW, Holst JJ, Davies MJ

During clinical trials, the effects of tesofensine are typically assessed over a specific period of time, often several weeks or months, to evaluate its effectiveness for the intended purpose

Human drug compounding: Policies and rules