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Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

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10 In an experiment performed on human colon circular muscular strips taken from normal subjects, it was found that GLP-1R is expressed in the human colon and when activated by exogenous GLP-1 it results in an inhibitory effect on the large intestine motility through nitric oxide neural release

Increased Fat Burn : Some studies suggest GLP-1 medications help shift metabolism towards greater fat utilization ( PubMed )