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Back Ferguson, D (20 April 2025) 'The end of WeightWatchers

When combined with resistance training, Zone 2 cardio, and metabolic optimization strategies, the reduction in VAT is profound

This raises questions as to whether obesity medications may need to be used long term

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& Ismail, K

A 5-year longitudinal study showed that FTO gene polymorphisms can lead to premature rebound of ghrelin (an appetite-promoting hormone) and a hypersensitive brain response to food stimuli, thereby weakening the appetite-suppressing effect of weight loss interventions [79]