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Liakas and his team
doi: 10.1016/s0968-0896(00)00263-7 20 Rose-MartelMHinckeMT
"Women with a high-cutoff vitamin B12 deficiency were 2.13 times as likely to be severely depressed," the study found
Findings: RCTSemaglutide vs Placebo for Alcohol Use Disorder in Adults, JAMA Psychiatry (2025) [PubMed abstract] Design: Randomized, placebo-controlled trial (N=48 | length = 9 weeks) in non-treatment-seeking adults with alcohol use disorder Treatment: Semaglutide (0.25 mg/week for 4 weeks, 0.5 mg/week for 4 weeks, and 1.0 mg for 1 week) vs Placebo Primary outcome: Objective alcohol self-administration (at baseline and between Weeks 8 and 9) measured as follows: a standardized procedure was used to estimate voluntary alcohol consumption and ability to delay drinking
The pairing you'll see most often is with TB-500 (Thymosin Beta-4 fragment) it's become the default recovery stack in the research community
However, TMAO was found to increase ICAM-1 expression together with tumor necrosis factor (TNF)- and interleukin (IL)-6 in macrophages (Geng et al., 2018)
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