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10.1016/j.fct.2019.110901 251 ZhangB.ChenZ

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The association of baseline antibodies (8587, 109, 110), baseline cytokine levels (65, 66, 111, 112), and immune cell changes (79, 83, 113116) suggests that humoral and cellular immunity play a role in some specific irAEs

Side effect frequencies are typically higher in the weight management indication (Zepbound) compared to the diabetes indication (Mounjaro), particularly at higher doses

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Within each zone, establish multiple injection spots at least one inch apart so you can rotate systematically