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GLP-1 receptor agonists (GLP-1RAs or GLP1s) like semaglutide have been proven to reduce body weight and lessen cardiovascular (CV) risk in patients with type 2 diabetes, butuntil SELECT was publishedthey had not been shown to improve cardiovascular outcomes in patients with a high BMI (aka the obese and overweight**) without diabetes

J Pediatr 1995

Cai Y, et al

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To determine the current activated by each compound, baseline IVs were measured in the buffer alone immediately prior to compound application and subtracted from the compound-elicited IV