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Further studies should be conducted to verify whether FOXO4-DRI is safe for human use

All procedures were conducted following the ethical standards and guidelines for laboratory animals set by the Peoples Republic of China and the Declaration of Helsinki

272 Overall, redox RO/NS modulates chromatin accessibility by altering HDAC/histone acetylation, necessitating further investigation into HDAC responses to redox signaling

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demonstrated that erastin-induced ferroptosis elevated lysosome-associated membrane protein 2a (LAMP2a) expression and promoted chaperone-mediated autophagy (CMA) while facilitating GPX4 degradation, suggesting a possible connection between autophagy and ferroptosis (Wu et al., 2019)

10.1002/jcp.27968 80