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In neuronal senescence model studies, the active ingredient of the product can cross the blood-brain barrier (and act directly on neurons in vitro), increase NAD+ levels in nerve cells, protect mitochondrial function, reduce neuronal apoptosis, and promote the synthesis and release of neurotransmitters (such as dopamine and acetylcholine), thereby improving signal transduction in nerve cells

Authors conclusions: Low quality evidence shows oral and IM vitamin B 12 having in terms of normalizing serum vitamin B similar effects 12 levels, but

People using B12 lipo shots often find it easier to stay consistent with planning and daily habits that support weight loss

Individuals with elevated baseline NNMT expression (common in obesity) may show more dramatic response to NNMT inhibition

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