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Key point: The formal list in 21 CFR 216.23 is different from FDAs Category 1 list of nominated substances under evaluation

Chandel, N.S., et al.,Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Ellingsgaard H, Hauselmann I, Schuler B et al (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

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Butyrate concentrations in the portal vein are ~18mol/l in a fasting human and 14-64mol/l in sudden death victims (86, 88), while the concentrations in peripheral blood are low to ~20% of portal vein concentrations (89)

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