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The brains restricted antioxidant capacity, high energy demand, high levels of transition metals, such as iron and copper, and a high concentration of polyunsaturated fatty acids which can be subjected to lipid peroxidation [103,104,105] make the nervous system particularly vulnerable to oxidative stress [106]

These results held up at the 52-week mark as well

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CIRS vs Mycotoxin Illness CIRS: Broad biomarker dysregulation Persistent innate immune activation Non-CIRS Mycotoxin Illness: Selective biomarker abnormalities May include immune sensitization without full systemic dysregulation This patients profile aligned with the latter