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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Marla S.S., Lee J., Groves J.T

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So, even though these two defenses against oxidative stress do not exhibit any significant downregulatory malfunction, a lack of their upregulation during a period of increased oxidative stress can contribute to the enhanced ROS experienced by the MUN placenta by not effectively removing enough superoxide and hydrogen peroxide from the placental environment

En conjunto, la evidencia disponible sobre estos mecanismos proviene de estudios in vitro y en modelos animales

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But alternatives exist for specific situations