Tirzepatide is a medication initially used for type 2 diabetes treatment that also demonstrates efficacy for weight loss and significant potential in reducing cardiovascular risks
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Once at the inner mitochondrial membrane, SS-31: Stabilizes cardiolipin: prevents the oxidative modification that disrupts membrane structure and ETC function Preserves cytochrome c interaction: cytochrome c is a protein that must remain loosely associated with cardiolipin for proper ETC function
Duration of action is how long the drug actually produces its effects in the body
While prior literature cites a 510% defect rate among women with pregestational diabetes, this study did not report any significant pregnancy losses following the use of GLP-1RA (92)
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