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In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]

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Thomsen MS, Kostrikov S, Routhe LG, Johnsen KB, Helgudttir SS, Gudbergsson JM, Andresen TL, Moos T (2025) Remodeling of the brain angioarchitecture in experimental chronic neurodegeneration

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Use it only with medications with which it is compatible, and follow the drug monograph for the appropriate diluent volume