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[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Agharezaee N, Hashemi M, Shahani M, Gilany K

The mainstay of treatment is levothyroxine replacement therapy , which aims to restore normal thyroid hormone levels

None have been tested in the rigorous, multi-phase clinical trial process that pharmaceutical GLP-1 medications undergo

Patients who assess results too early may underestimate the final outcome

Surgical treatment (browlift, blepharoplasty, partial or full facelift, and neck lift) may be needed to address loose skin in older patients or those with more significant facial sagging/aging

doi: 10.2337/db15-1527