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Name: glp-1 eye issues Drugs Could Double Risk of Severe Disease in Older Adults With Diabetes GLP-1s and Rapid Facial Aging:
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Description

Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]

2012 Wolfe RR et al

Lancet 394 (10193), 121130

10.1016/j.toxlet.2019.04.021 132

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