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The emerging gut-ovary-brain axis framework that ovarian dysfunction in PCOS is partly mediated by gut microbiome imbalance and altered neuroendocrine signaling is generating serious research attention

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Human Evidence (Limited but Promising) The most clinically relevant data comes from a 2016 study by Choi et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.N-acetylcysteine attenuates alcohol-induced oxidative stress in the rat

49 therefore suggested an important role of the residue as a gatekeeper to modify the reactivity of reducing or alkylating agents