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42 , 43 It is possible that greater effect on plasma cysteine level might have been achieved with higher dosing of cysteine, but there are limited data for tolerability of oral L-cysteine above single doses of 3g

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To investigate thrombosis mechanisms, the collagen gel was perfused with fluorescein isothiocyanate (FITC)-conjugated antibodies against VWF

Other assessments included changes in laboratory parameters (including but not limited to haematology and biochemistry), and physical examination, vital signs and ECG

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