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The results of studies confirming a high efficacy of PCSK9 inhibitors administered immediately after an ACS (the EVOPACS and EVACS studies with evolocumab [179, 180] and the VCU-alirocRT study with alirocumab [181]) are also worth noting, as they were the starting point for recommendation concerning initiation of treatment with PCSK9 inhibitors during hospitalisation (recommendation level IIa C) in the most recent ESC/EAS 2019 guidelines [9]