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Our previous study also showed that INKO mice have a different gut microbiota composition than their counterparts under a regular chow diet, suggesting that intestinal NAD + biosynthesis is involved in maintaining gut microbiota homeostasis and possibly contributing to the reduced GLP-1 production (unpublished data)

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When to Startand When Not To According to the package insert, GLP-1 therapy for obesity is indicated for individuals with a BMI 27 with a weight-related condition, or a BMI 30 alone

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Similarly, Eric Polley, PhD, a UChicago data science and public health expert, recently led a study published in Nature Cardiovascular Research that used statistical modeling to emulate a clinical trial comparing the effects of four different classes of diabetes medication in patients with moderate cardiovascular risk

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