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Acknowledgements We would like to thank Qiulin Tang for her assistance in preparing the manuscript

In line with this possibility, it has been shown that only a percentage of LepR-expressing neurons, including POMC and AgRP neurons, change their resting membrane potential after leptin application 29, 30

It works by activating melanocortin receptors in the brain to enhance sexual desire and arousal

This can lead to the formation of reactive oxygen species (ROS)

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& Magistretti, P