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Some patients rely on canes or walkers to support mobility at this stage

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However, subsequent salvage therapy with bevacizumab and continuation of the KD led to a response in six out of seven patients, and the authors confirmed in a mouse experiment that the combination of KD and bevacizumab, but not the KD alone, was superior to bevacizumab combined with standard chow with respect to survival and tumor size

Even with weekly injections for a full year, the cumulative weekly B6 dose from the compound alone ranges from 5 to 10 mg, far below the levels associated with neuropathy