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Funding This study was sponsored by CorEvitas, LLC, and the analysis and all manuscript-related activities were funded by Johnson & Johnson

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At a dose of 100 g/ml, the extract displayed inhibition on the PGE2, NO, IL-6, TNF-, and IL-1 expression and the activation of p38 MAPK, extracellular signal-regulated kinase (ERK), and JNK in LPS-activated RAW 264.7 cells

Ferroptosis is a new direction for prostate cancer treatment The phosphatase and tensin homolog (PTEN) deleted on chromosome 10 gene is a tumor suppressor gene discovered in recent years

426,427 In a low pH environment, fusogenic peptides undergo pH-dependent conformational changes to form -helices, which insert into the endosomal membrane, causing instability and decomposition of the membrane structure