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Alternative weight management approaches include specialist dietetic support, lifestyle interventions, alternative pharmacotherapy (with caution), or bariatric surgery with multidisciplinary assessment for suitable candidates

Dongiovanni P, Stender S, Pietrelli A, Mancina RM, Cespiati A, Petta S, Pelusi S, Pingitore P, Badiali S, Maggioni M, et al

Given the small sample size of this Study, it was not sufficiently powered for statistical significance analysis, which will be a key part of any expanded studies with DehydraTECH GLP-1 undertaken in the future

A., Rstam, L., Larsson, C

Historically, however, certain weight-loss agents were excluded

The WHO's December 2025 guidelines define long-term use as continuous treatment for six months or more, often years