As organisms age, these cells become senescent (dormant) and less capable of repairing damage
Mitochondrial biogenesis is involved in the regulation transcription of the mitochondrial and nuclear DNA-encoded genes
Histone H3K18 lactylation and upregulation of METTL3 and m6A levels in the mouse brain, along with increased LCN2 protein levels, activated astrocytes to undergo pro-inflammatory type A1 transformation (Gao et al., 2025)
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