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Not only is it a naturally occurring peptide with an established safety profile, but it's also available in meaningful concentrations that may help with age management
Use: For moisturizing products, reducing wrinkles in the form of gels, serums, lotions or creams
Interestingly, DA may also directly inhibit mitochondrial respiration [103] and DA oxidation generates toxic quinones and ROS leading to mitochondrial dysfunction [104]
PGC-1 has been identified as a master transcription factor that regulates a number of vital processes, including those related to mitochondrial antioxidant and clearance systems, as well as biogenesis