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Removing Dangerous Toxins from the Body As the liver snags toxins out of circulation, it must prepare them for disposal

It is naturally produced by the body, but levels may vary due to lifestyle, environmental exposure, and metabolic demands

Key Nutrient Depleted by Acetaminophen Glutathione the bodys primary antioxidant and detoxification molecule Why Glutathione Depletion Increases Liver Toxicity Risk Acetaminophen is metabolized in the liver through pathways that consume glutathione, a compound essential for neutralizing oxidative stress, detoxifying hormones and chemicals, and protecting cells from damage

Therefore, accelerated oxidation of biomolecules acts both as a product and causal for disease manifestation which is further exacerbated by failure of antioxidant system and loss of redox sensing capabilities of chaperone DJ-1 18,19

The concentration difference is not marginal

Eur J Nutr 2015 Mar;54(2):251-263