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Under normoxia, HIF-1 is degraded through proteasomes

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Cell lines and culture conditions HepG2 cells, a human hepatoma cell line, were obtained from the American Type Culture Collection (Manassas, VA) and were cultured in Dulbeccos modified Eagles medium (DMEM) containing 10% (v/v) fetal bovine serum, 2 mM glutamine, 5 U/mL penicillin, and 50 g/mL streptomycin at 37 C in a humidified O 2 /CO 2 (19:1) atmosphere

The repair-category comparison should remain catalog-field based

The usual course of treatment is 4 sessions over 4 to 6 weeks, with monthly maintenance

The peptide appears to regulate cell migration through its interaction with actin, a protein important for cell structure and movement