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In addition to symptom control by optimization of lifestyle and pharmacological therapy with proton pump inhibitors, chemopreventive strategies based on NSAIDs and statins are currently being investigated for BE management

J Mol Evol 90:95113 Koonin EV, Krupovic M (2019) Origin of programmed cell death from antiviral defense

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Outcomes Assessment of Nutriceutical Therapy

Based on the calcium dependence of calcineurin (CaN), calcium further serves as a second messenger to drive the CaN/nuclear factor of activated T cells (NFAT) pathway, participating in osteoblast proliferation, differentiation, and apoptosis (96)