In an effort to harness these protective effects, we have designed neuroprotective peptides from PEDF, namely 17-mer and its variant H105A, which target PEDF-R and are involved in mitigating calcium overload in degenerating photoreceptors associated with RP 29,30,31,32,33
How long it takes to fully work depends on what the condition is
The biggest concern around the safety of microdosing is if patients are doing it without the knowledge of their treating team (such as their GP, dietitian and pharmacist)
However, switching medications is a clinical decision that should be made with your provider based on your individual health profile
A., & Cuellar, T
No head-to-head trial has compared them, so better cannot be answered directly