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Post-bariatric surgery GLP-1 use represents a growing clinical niche without standardized guidelines, requiring individualized decision-making and close multi-specialty collaboration

Note that Lilly described this transition from tirzepatide to orforglipron as ATTAIN-MANTAIN, somewhat signalling they embrace the induction-maintenance model

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72 It has been suggested that this lack of ghrelin suppression may lead to higher food consumption and add to the pathophysiology of obesity

However, in the long term, patients suffering from chronic pain may find that their ability to perform tasks and their quality of life decrease

Stephen Sinatra: When I was on the telephone with him, it was absolutely incredible