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But he added that it would not surprise him if medications so closely tied to the bodys energy systems also shaped human emotions and social interactions
Notably, GLP-1-producing neurons within the nucleus tractus solitarius (NTS) project axons to the VTA and other limbic structures, further embedding GLP-1 signaling within neural networks that regulate reward and motivation (Llewellyn-Smith et al., 2011
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It also indirectly increases insulin sensitivity in skeletal muscle by promoting microvessel recruitment, which may enhance local insulin action [69]
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