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4 A study of two participants cannot establish: The frequency of uncommon adverse events Safety across different ages or health conditions Safety with other medicines or substances Long-term safety Safety through other routes Clinical effectiveness The authors themselves stated that further studies were needed
3 NAFLD is bidirectionally associated with components of metabolic syndrome
Preclinical models converge on immuneinflammatory signaling, HPA axis dysregulation and neurotransmitter alterations as recurrent mechanistic pathways (Ravi et al., 2021
A weakened gut barrier allows bacterial components to leak into the bloodstream, interferes with metabolic function, and may result in poor blood sugar regulation, struggles with weight management, food cravings, brain fog, and energy crashes after meals