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The STEP and SUSTAIN trial data provide robust evidence of systemic anti-inflammatory effects

Essential role of excessive tryptophan and its neurometabolites in fatigue

Treatment with GLP-1 RAs in these individuals may have corrected this subtle metabolic dysfunction, improving systemic energy balance, reducing inflammation, and potentially enhancing motor function, as an indirect result

Lipoic acid can chelate (bind) with some pro-oxidant minerals to provide detoxification in the organism and neutralize these minerals

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However, be careful not to exceed the recommended dose, as too much L-Carnitine can cause side effects like diarrhea and nausea