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A total of 100 nM ABHD11-Flag was added to 100 M of the substrates (OGDHc-E2 peptides or succinyl-CoA) in assay buffer (50 mM TrisHCl pH 7.4, 100 mM NaCl) in 1.5 ml Eppendorf tubes for each condition on ice

In these settings, the formulation is often administered as an IV therapy infusion or a guided subcutaneous protocol (often structured as a 6- or 12-week regimen, injecting five days a week)

Lyophilized (powder) DSIP should be stored in the freezer at -20C for maximum stability

JAMA 333 , 113114 (2025)

Ishida J, Saitoh M, Ebner N, Springer J, Anker SD, von Haehling S

Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, et al