Because of the acidic environment of phagosomes, O 2 is dismutated into H 2 O 2 , which is subsequently converted to other ROS [19, 20]
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In contrast, T cells preferentially migrate to the lesion boundary, with a marked increase in a few days after ischemia, reaching a peak within one week and persisting for months (71)
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Some patients also explore advanced options like high dose vitamin C, alpha lipoic acid, NAD infusion therapy, ozone therapy, or oxygen treatment as part of a broader infusion plan