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(2006) Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: The prospect of transmeningeal pharmacotherapy for intractable focal epilepsy

Abstract The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are released from enteroendocrine cells in response to the presence of nutrients in the small intestines

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When epithelial cells receive specific signals released by the cells that constitute their stromal microenvironment, these signalling pathways can be activated [83]

They work through effects on the gastrointestinal and central nervous system circuits, the circuits that drive overeating