Sandler: Given that SGLT2 inhibitors are of a smaller molecular weight, they have the potential to cross the placenta
In the heart, validated studies find the receptor concentrated in the sinoatrial node, which explains the modest increase in heart rate, and in atrial myocytes, where it stimulates the release of atrial natriuretic peptide
Shared decision-making that weighs potential benefits against individual risk factors ensures appropriate patient selection and optimizes treatment outcomes
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Liraglutide 3.0 mgs efficacy in obesity was assessed in the Satiety and Clinical Adiposity-Liraglutide (SCALE) Obesity and Prediabetes and SCALE-diabetes trials [15,41]
