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More to learn about the effects of semaglutide (GLP-1 RA) Science is still learning about how semaglutide (GLP-1 RA) drugs affect the body, including how they may impact the way you respond to food

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The Science: How HRT and GLP-1's Work Together for Midlife Weight Loss During peri-menopause and menopause, declining estrogen levels trigger significant metabolic shifts

Evidence from randomized controlled trials suggests that OA-related knee pain and function improve with semaglutide but not with liraglutide treatment, and observational studies suggest that GLP-1RA use reduces the risk of surgery for knee OA

Available from: Holmes GM, Browning KN, Tong M, Qualls-Creekmore E, Travagli RA (2009) Vagally mediated effects of glucagon-like peptide 1: in vitro and in vivo gastric actions