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Exogenous supplement of glucagon like peptide-1 protects the heart against aortic banding induced myocardial fibrosis and dysfunction through inhibiting mTOR/p70S6K signaling and promoting autophagy

The mechanism was proposed to be associated with melanin dispersion mediated by the pyran ring of the flavonoid chemical structure and the acceleration of epidermal turnover (139)

FIGURE 3 Conclusion The use of botanical drugs as a part of treatment has been a practice since ancient times, and it is being imposed in this era with the urge of evaluating their mechanism of action and their associated safety profile

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