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Many factors affect sleep quality, including stress, other medications, caffeine intake, screen time, and underlying sleep disorders such as sleep apnoea or restless legs syndrome

The goal is not only to prevent deficiency but also to support better energy metabolism and more effective fat-burning

Riederer, M., Erwa, W., Zimmermann, R., Frank, S

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Baseline measurements should confirm AMPK suppression (reduced phosphorylation status in muscle or liver) and NAD+ depletion (low tissue NAD+ levels or elevated NNMT enzymatic activity)

Activation of 3-AR via Gs cAMP PKA phosphorylation of hormone-sensitive lipase (HSL) leads to: Splitting of triglycerides into free fatty acids + glycerol Release of fatty acids from adipose tissue into the blood Increased oxidation of fatty acids in mitochondria (muscle, liver) Heffernan et al