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A commonly referenced guideline A daily deficit of around 500 calories may lead to gradual weight loss of approximately 0.40.5 kg per week

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Should Phase 3 data prove favourable, a regulatory submission could follow, though the timing remains uncertain and no predictions should be drawn from the approval timelines of other medicine classes

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This case occurred during a study in which the pills dosage was rapidly increased, and Pfizer stated that its decision was based on a thorough review of all clinical data and regulatory feedback