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Reduces Liver Fat Non-alcoholic fatty liver disease (NAFLD) often coexists with unhealthy lipid profiles

A landmark trial found that participants on the maximum maintenance dose lost approximately 17% of their body weight over 68 weeks, compared to roughly 10% on lower doses

Insulin Resistance: Unstable blood sugar levels can prevent the body from efficiently burning stored fat

As of mid-2025, retatrutide does not have an approved brand name, as it has not yet received marketing authorisation from any regulatory body, including the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK or the European Medicines Agency (EMA)

( 10.1210/en.2018-00004) [DOI] [PMC free article] [PubMed] [Google Scholar] 38.Yamamoto H, Lee CE, Marcus JN, Williams TD, Michael Overton JM, Lopez ME, Hollenberg AN, Baggio L, Saper CB, Drucker DJet al