Accessed October 4, 2011
[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Lee Y.-C., Wu L.-C., Wu V.-C., Chang C.-H
52 Interestingly, low zinc levels have been associated with pediatric inflammatory bowel disease 55 and increased inflammation in animal models of colitis 56 and zinc supplementation appears to be protective of bowel inflammation in clinical 57 and animal studies
Specifically in this trial, and in no other trials, SGLT2i treatment was combined with exenatide treatment
In the intestine, if HDAC is overexpressed, the balance of gene expression is disrupted and cell proliferation is abnormal, which eventually leads to tumorigenesis ( In particular, SCFAs contribute significantly in the fight against intestinal inflammation by promoting T reg cells differentiation through the inhibition of HDACs
Thus, incorporating fermentable fiber into the diet may support the growth of beneficial gut microbiota and exert prebiotic effects (355)